工程科學前沿講壇第330講:美國醫學與生物工程院會士Lijie Grace Zhang學術講座

作者:宋樹豐 來源:航空航天學院  瀏覽次數: 發布日期:2019/06/11 14:52:13

講座題目:Integrating Advanced 3D/4D Bioprinting and Nanotechnology for Complex Tissue Regeneration

主  講  人:Dr. Lijie Grace Zhang

講座時間:2019年06月14日 10時00分

講座地點:重慶大學A區理科樓205會議室

講座內容:

        As an emerging tissue manufacturing technique, 3D bioprinting offers great precision and control of the internal architecture and outer shape of a scaffold, allowing for close recapitulation of complicated structures found in biological tissue. In addition, 4D bioprinting is a highly innovative additive manufacturing process to fabricate pre-designed, self-assembly structures with the ability to transform from one state to another directly off the bioprinter. The term “4D” refers to the time-dependent dynamic process triggered by specific stimulation according to predesigned requirements. However, current 3D/4D bioprinting  d additive manufacturing technologies are hindered by the lack of advanced smart “inks”. Therefore, the main  ive of our research is to develop novel biologically inspired nano or smart inks and advanced 3D/4D bioprinting techniques to fabricate the next generation of complex tissue constructs (such as vascularized tissue, neural tissue and osteochondral tissue). For this purpose, we designed and synthesized innovative biologically inspired nanomaterials (i.e., self-assembly materials, and conductive carbon nanomaterials) and smart natural materials. Through 3D/4D bioprinting in our lab, a series of biomimetic tissue scaffolds were successfully fabricated. Our results show that these bioprinted nano or smart scaffolds have not only improved mechanical properties but also excellent cytocompatibility properties for enhancing various cell growth and differentiation, thus promising for complex tissue/organ regeneration.

主講人簡介:

        Dr. Lijie Grace Zhang于布朗大學獲得生物醫學工程博士學位,先后在萊斯大學和哈佛醫學院進行博士后工作,隨后加入GW公司并擔任納米醫學與組織生物工程實驗室主任。Lijie Grace Zhang博士為美國醫學與生物工程學會會士,曾獲美國機械工程師學會Sia Nemat-Nasser Early Career Award、美國國家衛生研究院Director’s New Innovator Award、Young Innovator in Cellular and Molecular Bioengineering、美國骨骼與礦物質研究協會John Haddad Young Investigator Award真人娱乐平台下载安装、Early Career Award from the International Journal of Nanomedicine等獎項真人娱乐平台下载安装。主要科研方向包括3D/4D生物打印、納米生物材料、組織工程、生物力學和乳腺癌骨轉移。出版專著3部,發表期刊/會議論文逾125篇,獲得7項發明專利授權,在學術會議、科研院所學術報告超過310次,擔任Materials Science and Engineering C: Materials for Biological Applications, International Journal of Nanomedicine, ASME Journal of Engineering and Science in Medical Diagnostics and Therapy等國際期刊副主編/編輯。

        Dr. Lijie Grace Zhang obtained her Ph.D. in Biomedical Engineering at Brown University. Dr. Zhang joined GW after finishing her postdoctoral training at Rice University and Harvard Medical School. She is the director of the Bioengineering Laboratory for Nanomedicine and Tissue Engineering at GW. Dr. Zhang is the Fellow of the American Institute for Medical and Biological Engineering (AIMBE). She has received the ASME Sia Nemat-Nasser Early Career Award, NIH Director’s New Innovator Award, Young Innovator in Cellular and Molecular Bioengineering, John Haddad Young Investigator Award by American Society for Bone and Mineral Research, and Early Career Award from the International Journal of Nanomedicine, etc. Her research interests include 3D/4D bioprinting, nanobiomaterials, tissue engineering, biomechanics, and breast cancer bone  stasis. Dr. Zhang has authored 3 books, over 125 journal papers, book chapters and conference proceedings, 7 patents and has presented her work on over 310 conferences, university and institutes. She also serves as the Editor of Materials Science and Engineering C: Materials for Biological Applications; Associate Editor-in-Chief of International Journal of Nanomedicine; and Associate Editor of ASME Journal of Engineering and Science in Medical Diagnostics and Therapy.

主辦單位:工程學部

協辦單位:航空航天學院





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